Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice.

SCH 39304 was compared with fluconazole and ketoconazole in a systemic Candida albicans infection in mice (10(6) CFU per mouse). Results were based on survival rates and CFU in kidneys following once-daily oral treatment of 2, 5, or 10 days duration. In normal mice, SCH 39304 (dose to reduce kidney...

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Main Authors: Cacciapuoti, A, Loebenberg, D, Parmegiani, R, Antonacci, B, Norris, C, Moss, E L, Menzel, F, Yarosh-Tomaine, T, Hare, R S, Miller, G H
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189227/
https://ncbi.nlm.nih.gov/pubmed/1590702
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