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Hematopoietic Stem Cell Aging: Mechanism and Consequence

Advancing age is frequented by the onset of a variety of hematological conditions characterized by diminished homeostatic control of blood cell production. The fact that upstream hematopoietic stem and progenitor cells are obligate mediators of homeostatic control of all blood lineages, has implicat...

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Bibliographic Details
Main Authors: Rossi, Derrick J., Bryder, David, Weissman, Irving L.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892213/
https://ncbi.nlm.nih.gov/pubmed/17275237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2006.11.019
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