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An improved method for identifying functionally linked proteins using phylogenetic profiles

BACKGROUND: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein complexes or metabolic pathways. Various existing methods measure similarity between two profiles and, hence, the likeliho...

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Autori principali: Cokus, Shawn, Mizutani, Sayaka, Pellegrini, Matteo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892086/
https://ncbi.nlm.nih.gov/pubmed/17570150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-S4-S7
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