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Prior infection with a nonpathogenic chimeric simian-human immunodeficiency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus.

Prior infection with a nef-deleted simian immunodeficiency virus (SIV) protects macaques not only against a homologous pathogenic SIV challenge but also against challenge with a chimeric SIV expressing a human immunodeficiency virus type 1 env gene (SHIV). Since this SHIV is itself nonpathogenic, we...

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Udgivet i:J Virol
Principais autores: Letvin, N L, Li, J, Halloran, M, Cranage, M P, Rud, E W, Sodroski, J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189207/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4569-4571.1995
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