Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence

BACKGROUND: Potential therapeutic use of mesenchymal stem cells (MSCs) is likely to require large-scale in vitro expansion of the cells before transplantation. MSCs from adipose tissue can be cultured extensively until senescence. However, little is known on the differentiation potential of adipose...

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Bibliografiske detaljer
Main Authors: Noer, Agate, Boquest, Andrew C, Collas, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892011/
https://ncbi.nlm.nih.gov/pubmed/17535427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-18
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