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Enhanced virus resistance of transgenic mice expressing the human MxA protein.

MxA is a GTPase that accumulates to high levels in the cytoplasm of interferon-treated human cells. Expression of MxA cDNA confers to transfected cell lines a high degree of resistance against several RNA viruses, including influenza, measles, vesicular stomatitis, and Thogoto viruses. We have now g...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Pavlovic, J, Arzet, H A, Hefti, H P, Frese, M, Rost, D, Ernst, B, Kolb, E, Staeheli, P, Haller, O
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769712/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4506-4510.1995
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