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Deletion of 11q23 and Cyclin D1 Overexpression Are Frequent Aberrations in Parathyroid Adenomas

Hyperparathyroidism may result from parathyroid hyperplasia or adenoma, or rarely from parathyroid carcinoma. Pericentromeric inversion of chromosome 11 that results in activation of the PRAD1/cyclin D1 gene and tumor suppressor gene loss have been described as genetic abnormalities in the evolution...

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Bibliografiska uppgifter
Huvudupphovsmän: Hemmer, Samuli, Wasenius, Veli-Matti, Haglund, Caj, Zhu, Ying, Knuutila, Sakari, Franssila, Kaarle, Joensuu, Heikki
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891928/
https://ncbi.nlm.nih.gov/pubmed/11290553
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