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A herpesvirus saimiri protein required for interleukin-2 independence is associated with membranes of transformed T cells.

A region of the herpesvirus saimiri genome encoding an mRNA with two open reading frames (ORFs) has been identified to be essential for transformation of T cells. Deletion of either ORF resulted in the loss of transforming ability. ORF-1 has been shown to code for a collagen-like oncoprotein. This s...

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Publicado en:J Virol
Autores principales: Lund, T, Medveczky, M M, Geck, P, Medveczky, P G
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4495-4499.1995
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