Inverse Relationship between Microsatellite Instability and K-ras and p53 Gene Alterations in Colon Cancer

Some studies have shown an inverse relationship between microsatellite instability in colon cancer and mutations in p53 and K-ras, whereas others have not. We therefore evaluated these features in a population-based sample of 496 individuals with colon cancer. Microsatellite instability was determin...

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Detalhes bibliográficos
Main Authors: Samowitz, Wade S., Holden, Joseph A., Curtin, Karen, Edwards, Sandra L., Walker, Adrianne R., Lin, Heather A., Robertson, Margaret A., Nichols, Melanie F., Gruenthal, Kristin M., Lynch, Beverly J., Leppert, Mark F., Slattery, Martha L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891913/
https://ncbi.nlm.nih.gov/pubmed/11290569
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