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Proliferating Bile Duct Epithelial Cells Are a Major Source of Connective Tissue Growth Factor in Rat Biliary Fibrosis

Connective tissue growth factor (CTGF) is a downstream mediator of transforming growth factor-β1 (TGF-β1) and thus a potential target for antifibrotic treatment strategies. CTGF is up-regulated in disorders such as atherosclerosis, scleroderma, and fibrosis of kidneys and lungs. We investigated the...

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Bibliografski detalji
Glavni autori: Sedlaczek, Nicolai, Jia, Ji-Dong, Bauer, Michael, Herbst, Hermann, Ruehl, Martin, Hahn, Eckhart G., Schuppan, Detlef
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891909/
https://ncbi.nlm.nih.gov/pubmed/11290541
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