Origin and Structural Evolution of the Early Proliferating Oval Cells in Rat Liver

We have analyzed the histological changes in rat liver after 2-acetylaminofluorene (AAF) administration. The data demonstrate that AAF-induced oval cells were preferentially generated by proliferation of the terminal biliary ductules that we suggest constitute the primary hepatic stem cell niche. Th...

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Détails bibliographiques
Auteurs principaux: Paku, Sandor, Schnur, Janos, Nagy, Peter, Thorgeirsson, Snorri S.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2001
Sujets:
Regular Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891899/
https://ncbi.nlm.nih.gov/pubmed/11290549
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