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Isolation and characterization of a syncytium-inducing, macrophage/T-cell line-tropic human immunodeficiency virus type 1 isolate that readily infects chimpanzee cells in vitro and in vivo.

Fresh human immunodeficiency virus type 1 (HIV-1) isolates from patients with AIDS were screened for infectivity in chimpanzee peripheral blood mononuclear cells (PBMC) to identify strains potentially able to generate high virus loads in an inoculated animal. Only 3 of 23 isolates obtained were infe...

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Publicat a:J Virol
Autors principals: Shibata, R, Hoggan, M D, Broscius, C, Englund, G, Theodore, T S, Buckler-White, A, Arthur, L O, Israel, Z, Schultz, A, Lane, H C
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769705/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4453-4462.1995
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