Synergistic inhibition of human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion and infection by an antibody to CD4 domain 2 in combination with anti-gp120 antibodies.

Antibodies to several epitopes of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120-gp41) can synergize in inhibiting HIV-1 infection. In the present study we tested the ability of a monoclonal antibody (MAb), 5A8, which interacts with CD4 domain 2, and other CD4-specific...

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Pubblicato in:	J Virol
Autori principali:	Burkly, L, Mulrey, N, Blumenthal, R, Dimitrov, D S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769687/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.7.4267-4273.1995
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