Transient Loss of High-Level Mupirocin Resistance in Staphylococcus aureus Due to MupA Polymorphism

Spontaneous loss of MupA-mediated high-level mupirocin resistance was observed in Staphylococcus aureus, although the isolate gave a PCR-positive test result for mupA. Sequencing of the mupA gene identified a single base-pair deletion that resulted in a frameshift mutation and loss of functional pro...

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Bibliographic Details
Main Authors: Driscoll, Daniel G., Young, Casey L., Ochsner, Urs A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891366/
https://ncbi.nlm.nih.gov/pubmed/17438053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00241-07
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