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Discovery of parasite virulence genes reveals a unique regulator of chromosome condensation 1 ortholog critical for efficient nuclear trafficking

Eukaryotic parasites are a leading cause of morbidity and mortality worldwide, yet little is known about the genetic basis of their virulence. Here, we present a forward genetic screen to study pathogenesis in the protozoan parasite Toxoplasma gondii. By using modified signature-tagged mutagenesis,...

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Detalhes bibliográficos
Main Authors: Frankel, Matthew B., Mordue, Dana G., Knoll, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891257/
https://ncbi.nlm.nih.gov/pubmed/17535896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701893104
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