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Dissection of the components for PIP(2) activation and thermosensation in TRP channels

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) plays a central role in the activation of several transient receptor potential (TRP) channels. The role of PIP(2) on temperature gating of thermoTRP channels has not been explored in detail, and the process of temperature activation is largely unexplain...

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Main Authors: Brauchi, Sebastian, Orta, Gerardo, Mascayano, Carolina, Salazar, Marcelo, Raddatz, Natalia, Urbina, Hector, Rosenmann, Eduardo, Gonzalez-Nilo, Fernando, Latorre, Ramon
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891241/
https://ncbi.nlm.nih.gov/pubmed/17548815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703420104
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