Increasing transduction efficiency of recombinant murine retrovirus vectors by initiation of endogenous reverse transcription: potential utility for genetic therapies.

Reverse transcription of retroviral genomic RNA in a target cell is influenced by cellular factors, including the concentration of deoxyribonucleoside triphosphates (dNTPs). In addition, recent data have demonstrated that reverse transcription can be driven within human immunodeficiency virus type 1...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Zhang, H, Duan, L X, Dornadula, G, Pomerantz, R J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189120/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7538178/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.6.3929-3932.1995
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