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Translation but not the encoded sequence is essential for the efficient propagation of the defective interfering RNAs of the coronavirus mouse hepatitis virus.

The defective interfering (DI) RNA MIDI of mouse hepatitis virus strain A59 (MHV-A59) contains a large open reading frame (ORF) spanning almost its entire genome. This ORF consists of sequences derived from ORF1a, ORF1b, and the nucleocapsid gene. We have previously demonstrated that mutations that...

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Bibliographic Details
Published in:J Virol
Main Authors: van der Most, R G, Luytjes, W, Rutjes, S, Spaan, W J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7745722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.6.3744-3751.1995
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