Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.

Human immunodeficiency virus type 1 (HIV-1) isolates derived directly from clinical samples are usually unable to grow in cytokine-independent continuous cell lines, thus hindering the study of their biological features and their sensitivity to humoral and cellular protective immunity. To overcome t...

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Detalhes bibliográficos
Main Authors: Lusso, P, Cocchi, F, Balotta, C, Markham, P D, Louie, A, Farci, P, Pal, R, Gallo, R C, Reitz, M S
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189087/
https://ncbi.nlm.nih.gov/pubmed/7745720
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