Common genetic variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and late-onset Alzheimer's disease

Genome-wide linkage studies have defined a broad susceptibility region for late-onset Alzheimer's disease on chromosome 12, which contains the Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) gene, a coreceptor for Wnt signaling. Here, we report the association between common LRP6 vari...

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Detalhes bibliográficos
Main Authors: De Ferrari, Giancarlo V., Papassotiropoulos, Andreas, Biechele, Travis, Wavrant De-Vrieze, Fabienne, Avila, Miguel E., Major, Michael B., Myers, Amanda, Sáez, Katia, Henríquez, Juan P., Zhao, Alice, Wollmer, M. Axel, Nitsch, Roger M., Hock, Christoph, Morris, Chris M., Hardy, John, Moon, Randall T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890512/
https://ncbi.nlm.nih.gov/pubmed/17517621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603523104
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