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Selectivity in K(+) channels is due to topological control of the permeant ion's coordinated state
The selectivity filter of K(+) channels provides specific coordinative interactions between dipolar carbonyl ligands, water, and the permeant cation, which allow for selective flow of K(+) over (most importantly) Na(+) across the cell membrane. Although a structural viewpoint attributes K(+) selecti...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890482/ https://ncbi.nlm.nih.gov/pubmed/17519335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700554104 |
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