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Akt signalling through GSK-3β, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy

Skeletal muscle size is tightly regulated by the synergy between anabolic and catabolic signalling pathways which, in humans, have not been well characterized. Akt has been suggested to play a pivotal role in the regulation of skeletal muscle hypertrophy and atrophy in rodents and cells. Here we mea...

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Autori principali: Léger, Bertrand, Cartoni, Romain, Praz, Manu, Lamon, Séverine, Dériaz, Olivier, Crettenand, Antoinette, Gobelet, Charles, Rohmer, Paul, Konzelmann, Michel, Luthi, François, Russell, Aaron P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890416/
https://ncbi.nlm.nih.gov/pubmed/16916907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.116715
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