Akt signalling through GSK-3β, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy

Skeletal muscle size is tightly regulated by the synergy between anabolic and catabolic signalling pathways which, in humans, have not been well characterized. Akt has been suggested to play a pivotal role in the regulation of skeletal muscle hypertrophy and atrophy in rodents and cells. Here we mea...

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Главные авторы: Léger, Bertrand, Cartoni, Romain, Praz, Manu, Lamon, Séverine, Dériaz, Olivier, Crettenand, Antoinette, Gobelet, Charles, Rohmer, Paul, Konzelmann, Michel, Luthi, François, Russell, Aaron P
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2006
Предметы:
Skeletal Muscle and Exercise
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890416/
https://ncbi.nlm.nih.gov/pubmed/16916907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.116715
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