Immunohistochemical analysis of Mcl-1 and Bcl-2 proteins in normal and neoplastic lymph nodes.

The Bcl-2 protein blocks programmed cell death and becomes overproduced in many follicular non-Hodgkin's lymphomas as the result of t(14; 18) translocations involving the Bcl-2 gene. Mcl-1 is a recently discovered gene whose encoded protein has significant homology with Bcl-2 but whose function...

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Bibliographic Details
Main Authors: Krajewski, S., Bodrug, S., Gascoyne, R., Berean, K., Krajewska, M., Reed, J. C.
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890333/
https://ncbi.nlm.nih.gov/pubmed/8080035
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