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Toward detecting and identifying macromolecules in a cellular context: Template matching applied to electron tomograms

Electron tomography is the only technique available that allows us to visualize the three-dimensional structure of unfixed and unstained cells currently with a resolution of 6–8 nm, but with the prospect to reach 2–4 nm. This raises the possibility of detecting and identifying specific macromolecula...

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Autors principals: Böhm, Jochen, Frangakis, Achilleas S., Hegerl, Reiner, Nickell, Stephan, Typke, Dieter, Baumeister, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18903/
https://ncbi.nlm.nih.gov/pubmed/11087814
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