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Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1.

Certain human immunodeficiency virus type 1 (HIV-1) isolates are able to productively infect nondividing cells of the monocyte/macrophage lineage. We have used a molecular genetic approach to construct two different HIV-1 integrase mutants that were studied in the context of an infectious, macrophag...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Englund, G, Theodore, T S, Freed, E O, Engelman, A, Martin, M A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189028/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.3216-3219.1995
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