The N-terminal region of the adenovirus type 5 E1A proteins can repress expression of cellular genes via two distinct but overlapping domains.

The transforming E1A 12S and E1A 13S proteins of human adenovirus type 5 (Ad5) contain two and three conserved regions, respectively. In the present study, the contribution of sequences in the nonconserved N-terminal region of the E1A proteins to morphological transformation and to down-regulation o...

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Main Authors: Dorsman, J C, Hagmeyer, B M, Veenstra, J, Elfferich, P, Nabben, N, Zantema, A, van der Eb, A J
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188995/
https://ncbi.nlm.nih.gov/pubmed/7707522
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