Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers

Carbonic anhydrase XII (CA XII) is a transmembrane glycoprotein with an active extracellular CA domain that is overexpressed on cell surfaces of certain cancers. Its expression has been linked to tumor invasiveness. To characterize its catalytic properties, we purified recombinant secretory forms of...

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Autores principales: Ulmasov, Barbara, Waheed, Abdul, Shah, Gul N., Grubb, Jeffrey H., Sly, William S., Tu, Chingkuang, Silverman, David N.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC18897/
https://ncbi.nlm.nih.gov/pubmed/11121027
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