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Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers

Carbonic anhydrase XII (CA XII) is a transmembrane glycoprotein with an active extracellular CA domain that is overexpressed on cell surfaces of certain cancers. Its expression has been linked to tumor invasiveness. To characterize its catalytic properties, we purified recombinant secretory forms of...

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Main Authors: Ulmasov, Barbara, Waheed, Abdul, Shah, Gul N., Grubb, Jeffrey H., Sly, William S., Tu, Chingkuang, Silverman, David N.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18897/
https://ncbi.nlm.nih.gov/pubmed/11121027
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