Antibodies to the vitronectin receptor (integrin alpha V beta 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells.

The amino acid sequence Arg-Gly-Asp (RGD) is highly conserved on the VP1 proteins of different serotypes and subtypes of foot-and-mouth disease virus (FMDV) and is essential for cell attachment. This sequence is also found in certain extracellular matrix proteins that bind to a family of cell surfac...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Berinstein, A, Roivainen, M, Hovi, T, Mason, P W, Baxt, B
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7533862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2664-2666.1995
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