Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1.

We show that tick-transmitted Thogoto virus is sensitive to interferon-induced nuclear Mx1 protein, which is known for its specific antiviral action against orthomyxoviruses. Influenza virus-susceptible BALB/c mice (lacking a functional Mx1 gene) developed severe disease symptoms and died within day...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Haller, O, Frese, M, Rost, D, Nuttall, P A, Kochs, G
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2596-2601.1995
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