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Mutations in the DNA-binding and transcriptional activation domains of v-Myb cooperate in transformation.

The v-Myb protein encoded by avian myeloblastosis virus causes oncogenic transformation of monoblastic cells committed to the monocyte/macrophage lineage. v-Myb is a doubly truncated form of its normal cellular counterpart, c-Myb. In addition to its N- and C-terminal deletions, v-Myb contains a numb...

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Udgivet i:J Virol
Principais autores: Dini, P W, Eltman, J T, Lipsick, J S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188928/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2515-2524.1995
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