Immunogenic targeting of recombinant peptide vaccines to human antigen-presenting cells by chimeric anti-HLA-DR and anti-surface immunoglobulin D antibody Fab fragments in vitro.

To increase the inherently weak immunogenicity of synthetic peptide vaccines, we used recombinant DNA techniques to generate chimeras between immunogenic determinants of human immunodeficiency virus type 1 (HIV-1) gp120 and antibody Fab fragments reactive with surface structures displayed specifical...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Baier, G, Baier-Bitterlich, G, Looney, D J, Altman, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7533857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2357-2365.1995
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