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Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery.

Entry of human adenovirus into host cells involves interaction of virus particles with two distinct receptors. The initial binding event is mediated by the fiber protein, while subsequent interaction of the penton base protein with alpha v integrins promotes virus internalization and/or penetration....

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Huang, S, Endo, R I, Nemerow, G R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7533853/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2257-2263.1995
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