Cytomegalovirus-mediated induction of antisense mRNA expression to UL44 inhibits virus replication in an astrocytoma cell line: identification of an essential gene.

We have used an antisense RNA approach in the analysis of gene function in human cytomegalovirus (HCMV). An astrocytoma cell line (U373-MG) that is permissive for virus replication was permanently transfected with a construct bearing sequence from HCMV UL44 (coding for the major late DNA-binding pro...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ripalti, A, Boccuni, M C, Campanini, F, Landini, M P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188870/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2047-2057.1995
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