[2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1.

The [2',5'-bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino- 1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of ribofuranosylthymine, uridine, 5-bromouridine, 5-methylcytidine, inosine, and adenosine are potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) but...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Balzarini, J, Pérez-Pérez, M J, San-Félix, A, Velazquez, S, Camarasa, M J, De Clercq, E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.1073
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