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Modification of caffeine-induced injury in Ca2+-free perfused rat hearts. Relationship to the calcium paradox.

The pathogenesis of the calcium paradox has not been established. In calcium-free perfused hearts, caffeine, which releases calcium from the sarcoplasmic reticulum, causes severe myocardial injury, with creatine kinase (CK) release and contraction band necrosis similar in many respects to the calciu...

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Autori principali: Vander Heide, R. S., Altschuld, R. A., Lamka, K. G., Ganote, C. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888312/
https://ncbi.nlm.nih.gov/pubmed/3706496
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