Pharmacokinetics and tissue penetration of ampicillin and brobactam following oral administration of 2085P.

Eight healthy volunteers received a 1,000-mg single oral dose of 2085P which consisted of 800 mg of pivampicillin and 200 mg of brobactam. Concentrations of ampicillin and brobactam in plasma, inflammatory fluid, and urine were measured over the subsequent 24 h. Pivampicillin and brobactam were mode...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Wise, R, O'Sullivan, N, Johnson, J, Andrews, J M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324634/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.1002
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