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Lesions in the skin, intestine, and central nervous system induced by an antimetabolite of niacin.
Pellagra in the human is characterized by the clinical "three D's," namely, dermatitis, diarrhea, and dementia. Newborn mice that received a single intraperitoneal injection of 6-aminonicotinamide (6-AN) (50 mg/kg body weight), an antagonist of niacin, consistently developed lesions i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1888097/ https://ncbi.nlm.nih.gov/pubmed/2936253 |
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