Effects of deoxycoformycin in mice. III. A murine model reproducing multi-system pathology of human adenosine deaminase deficiency.

Adult AKR/J mice were treated with 10 micrograms/g or 100 micrograms/g 2'-deoxycoformycin, an adenosine deaminase inhibitor with chemotherapeutic potential. The thymus and adrenal glands were decreased in weight more than any other organ. Histologic and cytofluorographic analyses indicated pref...

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Bibliografiska uppgifter
Huvudupphovsmän: Ratech, H., Hirschhorn, R., Thorbecke, G. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1985
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1888086/
https://ncbi.nlm.nih.gov/pubmed/3872599
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