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Protease Modulation of the Activity of the Epithelial Sodium Channel Expressed in Xenopus Oocytes

We have investigated the effect of extracellular proteases on the amiloride-sensitive Na(+) current (I(Na)) in Xenopus oocytes expressing the three subunits α, β, and γ of the rat or Xenopus epithelial Na(+) channel (ENaC). Low concentrations of trypsin (2 μg/ml) induced a large increase of I(Na) wi...

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Détails bibliographiques
Auteurs principaux: Chraïbi, Ahmed, Vallet, Véronique, Firsov, Dmitri, Hess, Solange Kharoubi, Horisberger, Jean-Daniel
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887769/
https://ncbi.nlm.nih.gov/pubmed/9417140
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