Immature Dendritic Cells Acquire Cd8(+)Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli

The well defined, immature murine dendritic cell (DC) line D1 was used to study the role of DC maturation in CTL induction in vitro and in vivo. Maturation of D1 cells, characterized by markedly increased expression of MHC and costimulatory molecules, was induced by incubation with lipopolysaccharid...

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Main Authors: Schuurhuis, Danita H., Laban, Sandra, Toes, René E.M., Ricciardi-Castagnoli, Paola, Kleijmeer, Monique J., van der Voort, Ellen I.H., Rea, Delphine, Offringa, Rienk, Geuze, Hans J., Melief, Cornelis J.M., Ossendorp, Ferry
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
Fag:
Brief Definitive Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887717/
https://ncbi.nlm.nih.gov/pubmed/10880536
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