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Negative Regulation of T Cell Proliferation and Interleukin 2 Production by the Serine Threonine Kinase Gsk-3

Glycogen synthase kinase (GSK)-3 is a protein serine/threonine kinase that regulates differentiation and cell fate in a variety of organisms. This study examined the role of GSK-3 in antigen-specific T cell responses. Using resting T cells from P14 T cell receptor (TCR)-transgenic mice (specific for...

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Detalhes bibliográficos
Main Authors: Ohteki, Toshiaki, Parsons, Michael, Zakarian, Arsen, Jones, Russell G., Nguyen, Linh T., Woodgett, James R., Ohashi, Pamela S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887707/
https://ncbi.nlm.nih.gov/pubmed/10880530
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