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Cystic fibrosis transmembrane conductance regulator is vital to sperm fertilizing capacity and male fertility

Cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel, mutations of which cause cystic fibrosis, a disease characterized by defective Cl(−) and HCO(3)(−) transport. Although >95% of all CF male patients are infertile because of congenital bilateral absence of the vas defe...

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Detalhes bibliográficos
Main Authors: Xu, Wen Ming, Shi, Qi Xian, Chen, Wen Ying, Zhou, Chen Xi, Ni, Ya, Rowlands, Dewi Kenneth, Yi Liu, Guo, Zhu, Hu, Ma, Ze Gang, Wang, Xiao Fei, Chen, Zhang Hui, Zhou, Si Chang, Dong, Hong Shan, Zhang, Xiao Hu, Chung, Yiu Wa, Yuan, Yu Ying, Yang, Wan Xi, Chan, Hsiao Chang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887595/
https://ncbi.nlm.nih.gov/pubmed/17519339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609253104
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