Internal DNA pressure modifies stability of WT phage

dsDNA in bacteriophages is highly stressed and exerts internal pressures of many atmospheres (1 atm = 101.3 kPa) on the capsid walls. We investigate the correlation between packaged DNA length in λ phage (78–100% of WT DNA) and capsid strength by using an atomic force microscope indentation techniqu...

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Bibliographic Details
Main Authors: Ivanovska, Irena, Wuite, Gijs, Jönsson, Bengt, Evilevitch, Alex
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Physical Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887591/
https://ncbi.nlm.nih.gov/pubmed/17535894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703166104
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