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Mechanism of the 5-hydroxytryptamine 2A receptor-mediated facilitation of synaptic activity in prefrontal cortex

Classic hallucinogens such as lysergic acid diethylamide are thought to elicit their psychotropic actions via serotonin receptors of the 5-hydroxytryptamine 2A subtype (5-HT(2A)R). One likely site for these effects is the prefrontal cortex (PFC). Previous studies have shown that activation of 5-HT(2...

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Detalhes bibliográficos
Main Authors: Béïque, Jean-Claude, Imad, Mays, Mladenovic, Ljiljana, Gingrich, Jay A., Andrade, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887564/
https://ncbi.nlm.nih.gov/pubmed/17535909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700436104
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