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Sildenafil accelerates reentrainment of circadian rhythms after advancing light schedules
Mammalian circadian rhythms are generated by a master clock located in the suprachiasmatic nuclei and entrained by light-activated signaling pathways. In hamsters, the mechanism responsible for light-induced phase advances involves the activation of guanylyl cyclase, cGMP and its related kinase (PKG...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1887561/ https://ncbi.nlm.nih.gov/pubmed/17519328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703388104 |
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