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Sildenafil accelerates reentrainment of circadian rhythms after advancing light schedules

Mammalian circadian rhythms are generated by a master clock located in the suprachiasmatic nuclei and entrained by light-activated signaling pathways. In hamsters, the mechanism responsible for light-induced phase advances involves the activation of guanylyl cyclase, cGMP and its related kinase (PKG...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Agostino, Patricia V., Plano, Santiago A., Golombek, Diego A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887561/
https://ncbi.nlm.nih.gov/pubmed/17519328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703388104
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