Amino acid substitutions in the poliovirus maturation cleavage site affect assembly and result in accumulation of provirions.
The assembly of infectious poliovirus virions requires a proteolytic cleavage between an asparagine-serine amino acid pair (the maturation cleavage site) in VP0 after encapsidation of the genomic RNA. In this study, we have investigated the effects that mutations in the maturation cleavage site have...
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| Udgivet i: | J Virol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7853487/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.3.1540-1547.1995 |
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