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Dexamethasone inhibits induction of liver tumor necrosis factor-alpha mRNA and liver growth induced by lead nitrate and ethylene dibromide.

We have recently demonstrated that a single injection of the mitogen lead nitrate to rats induced a rapid increase of tumor necrosis factor-alpha (TNF-alpha) mRNA in the liver and suggested that this cytokine may be involved in triggering hepatocyte proliferation in this model of direct hyperplasia....

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Detalhes bibliográficos
Main Authors: Ledda-Columbano, G. M., Columbano, A., Cannas, A., Simbula, G., Okita, K., Kayano, K., Kubo, Y., Katyal, S. L., Shinozuka, H.
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887342/
https://ncbi.nlm.nih.gov/pubmed/7943184
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