Detection of RET proto-oncogene point mutations in paraffin-embedded pheochromocytoma specimens by nonradioactive single-strand conformation polymorphism analysis and direct sequencing.

The suitability of formalin-fixed and paraffin-embedded tumor material was evaluated for molecular analysis of the RET proto-oncogene. We analyzed exons 10, 11, and 16 for point mutations in seven sporadic and six multiple endocrine neoplasia (MEN) 2A-associated pheochromocytomas by a nonradioactive...

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Main Authors: Komminoth, P., Kunz, E., Hiort, O., Schröder, S., Matias-Guiu, X., Christiansen, G., Roth, J., Heitz, P. U.
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887320/
https://ncbi.nlm.nih.gov/pubmed/7943181
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