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Absence of HLA class I expression by Reed-Sternberg cells.

The reactive cell population in Hodgkin's disease consists of predominantly CD4+ helper T cells and lacks CD8+ cytotoxic T cells and natural killer cells. This lack of a CD8+ response is surprising in view of the expression of the latent Epstein-Barr viral protein LMP by Reed-Sternberg cells in...

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Detalhes bibliográficos
Main Authors: Poppema, S., Visser, L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887312/
https://ncbi.nlm.nih.gov/pubmed/7518195
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