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All-trans retinoic acid and extracellular Ca2+ differentially influence extracellular matrix production by human skin in organ culture.

Two-mm full-thickness punch biopsies of human skin were placed in organ culture in a serum-free, growth factor-free basal medium. Under conditions of low extracellular Ca2+ (0.15 mmol/L), the tissue quickly degenerated. However, degeneration was prevented when the extracellular Ca2+ concentration wa...

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Detalhes bibliográficos
Main Authors: Varani, J., Larson, B. K., Perone, P., Inman, D. R., Fligiel, S. E., Voorhees, J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886990/
https://ncbi.nlm.nih.gov/pubmed/8506950
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